kidney damage
Supervised Learning Models for Early Detection of Albuminuria Risk in Type-2 Diabetes Mellitus Patients
Muharram, Arief Purnama, Tahapary, Dicky Levenus, Lestari, Yeni Dwi, Sarayar, Randy, Dirjayanto, Valerie Josephine
Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes, adversely affects the kidneys, leading to kidney damage. Diagnosing diabetic nephropathy involves considering various criteria, one of which is the presence of a pathologically significant quantity of albumin in urine, known as albuminuria. Thus, early prediction of albuminuria in diabetic patients holds the potential for timely preventive measures. This study aimed to develop a supervised learning model to predict the risk of developing albuminuria in T2DM patients. The selected supervised learning algorithms included Na\"ive Bayes, Support Vector Machine (SVM), decision tree, random forest, AdaBoost, XGBoost, and Multi-Layer Perceptron (MLP). Our private dataset, comprising 184 entries of diabetes complications risk factors, was used to train the algorithms. It consisted of 10 attributes as features and 1 attribute as the target (albuminuria). Upon conducting the experiments, the MLP demonstrated superior performance compared to the other algorithms. It achieved accuracy and f1-score values as high as 0.74 and 0.75, respectively, making it suitable for screening purposes in predicting albuminuria in T2DM. Nonetheless, further studies are warranted to enhance the model's performance.
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AI mines EHR data to predict diabetic patients at risk for kidney damage, study finds
Artificial intelligence start-up Medial EarlySign in a new study has shown how the combination of AI and EHR data can facilitate early detection and treatment of kidney problems and can help slow down – or even prevent – progression to end-stage renal disease. Medial EarlySign's machine learning-based model analyzed dozens of factors residing in electronic health records, including laboratory test results, demographics, medications, diagnostic codes and others, to predict who might be at high risk for having renal dysfunction within one year. By isolating less than 5 percent of the 400,000 diabetic population selected among the company's database of 15 million patients, the algorithm was able to identify 45 percent of patients who would progress to significant kidney damage within a year, prior to becoming symptomatic, the start-up reported. This represents 25 percent more patients than would have been identified by commonly used clinical tools and judgment, the company contended. "Immense efforts are invested in developing treatment protocols to reduce the number of patients who will develop renal dysfunction due to diabetes," said Ran Goshen, MD, Medial EarlySign's chief medical officer.
- Health & Medicine > Therapeutic Area > Nephrology (1.00)
- Health & Medicine > Therapeutic Area > Endocrinology > Diabetes (0.95)
AI mines EHR data to predict diabetic patients at risk for kidney damage, study finds
Artificial intelligence start-up Medial EarlySign in a new study has shown how the combination of AI and EHR data can facilitate early detection and treatment of kidney problems and can help slow down – or even prevent – progression to end-stage renal disease. Medial EarlySign's machine learning-based model analyzed dozens of factors residing in electronic health records, including laboratory test results, demographics, medications, diagnostic codes and others, to predict who might be at high risk for having renal dysfunction within one year. By isolating less than 5 percent of the 400,000 diabetic population selected among the company's database of 15 million patients, the algorithm was able to identify 45 percent of patients who would progress to significant kidney damage within a year, prior to becoming symptomatic, the start-up reported. This represents 25 percent more patients than would have been identified by commonly used clinical tools and judgment, the company contended. "Immense efforts are invested in developing treatment protocols to reduce the number of patients who will develop renal dysfunction due to diabetes," said Ran Goshen, MD, Medial EarlySign's chief medical officer.
- Health & Medicine > Therapeutic Area > Nephrology (1.00)
- Health & Medicine > Therapeutic Area > Endocrinology > Diabetes (0.97)